Study Grant for Future Doctors of VCO, academic year 2024/25

We are pleased to inform you that the Livia and Vittorio Tonolli Foundation of Verbania has once again established a competition this year for the awarding of two study support grants, each worth €1,500, aimed at students from the VCO who have passed the admission test to the Faculty of Medicine and are officially enrolled in the first academic year 2024/25 at an Italian university.

Novelty in internal medicine. Focus on geriatry and cardiology

On Saturday 11th June 2022 at the Congressional Room of Hotel Regina Palace in Stresa, the concress News in internal medicine came to its end. Focus on geriatry and cardiologia The Course was accredited by the National ECM Committee to allow participants to acquire 5 training credits for the profession of Surgeon: Cardiology – Geriatria – Metabolic diseases and Diabetology – General Medicine (MMG) – Internal Medicine – Nephrology – Neurology. The E.C.M. certificate, indicating the number of credits awarded, will be sent within 90 days of the date of the training event.

Training objectives

Clinical documentation. Diagnostic and rehabilitative clinical-care pathways, assistant profiles – care profiles.

Programme of the conference

09.00 registration of participants and welcome coffee 09.45 Greeting from Authority 1st meeting INTERNAL AND GERIATRICAL MEDICINE Moderators: Fabio Di Stefano, Verbania and Patrizia Julita, Domodossola 10.15 Hands on. MEP Diagnoses of deep vein thrombosis Alessandra Togna, Verbania 10.45 SState of the art. DOACS in the treatment of deep venous thrombosis Fulvio Pomero, Alba 11.15 New concepts. Neurological diseases and dementia Fabio Di Stefano, Verbania 11.45 Focus. COVID 19 and thrombosis Mauro Campanini, Novara 12.15 Debate 12.45 Light Lunch 2th meeting CARDIOLOGY Moderators: Alessandro Lupi, Verbania – Maurizio Borzumati, Verbania e Giuseppe Placentino, Verbania 14.00 HHands on MEP ecocardiogram “FAST” Mariella Montano, Verbania 14.30 State of the art. Amiloidosis Stefano Perlini, Pavia 15.00New concepts. SGLT2 inhibitors and cardiac suppression Stefano Bertuol, Verbania 15.30 Focus. Interventional cardiology Alessandro Lupi, Verbania 16.00 Debate 16.30 Conclusions and closure of work

Scientific Directorate and Secretariat

Dr Fabio Di Stefano Primary of Intern Medicin and Geriatria, Verbania Hospital Dr Alessandro Lupi Primary of Intern Medicin and Geriatria, Verbania Hospital

General coordination

Livia and Vittorio Tonolli Foundation for cardiology and Multidisciplinary Sciences Livia e Vittorio Tonolli Prof. Giuseppe Riggio, Presidente Corso Nazioni Unite, 64 28925 Verbania Suna VB www.fondazionetonolli.it

Segreteria organizzativa e provider ECM

Victory Project Congressi Via Carlo Poma, 2 20129 Milano MI Tel. 02 89 05 35 24 – Fax 02 20 13 95 info@victoryproject.it www.victoryproject.it

Elogio della capacità di arrossire

a cura di: Fabio Gabrielli, Professore di Antropologia filosofica e Preside della Facoltà di Scienze umane della L.U. de S. Lugano

«La perdita della relazione umana (spontanea, reciproca, simbolica) è il fatto fondamentale delle nostre società. È su questa base che si assiste alla reiniezione sistematica di relazione umana – sotto forma di segni – nel circuito sociale e al consumo di questa relazione significata, di questo calore umano significato. L’hostess accompagnatrice, l’assistente sociale, l’ingegnere in relazioni pubbliche, la pin-up pubblicitaria, tutti questi apostoli funzionari hanno per missione secolare la gratificazione, la lubrificazione dei rapporti sociali attraverso il sorriso istituzionale. Dappertutto si vede la pubblicità imitare i modi della comunicazione privata, intima, personale. La pubblicità si sforza di parlare alla casalinga col linguaggio della casalinga di fronte, al dirigente e alla segretaria come il suo principale o il suo collega, a ciascuno di noi come un nostro amico, come il nostro Super-io, o come una voce interiore al modo della confessione. La pubblicità produce così intimità là dove non ce n’è, tra gli uomini, tra questi ultimi e i prodotti, secondo un vero processo di simulazione».

Paesaggi del dolore e della sofferenza

a cura di: Fabio Gabrielli, Professore di Antropologia filosofica e Preside della Facoltà di Scienze umane della L.U. de S. Lugano

Come è noto il dolore e la sofferenza disegnano profili esistenziali diversi. Il dolore presuppone passività, rinvia a cause, determina un male oggettivo ed è moralmente neutro; la sofferenza implica reattività, rinvia al reperimento di un senso/non senso e, quindi, è moralmente rilevante. In altri termini, il dolore è un evento oggettivo, un accadimento tragico, sul quale la coscienza esercita una riflessione (sofferenza) improntata ad una diversificata pluralità di tonalità affettive: dallo sgomento alla rabbia, dalla rassegnazione alla compassione, passando per l’angoscia, il mistero del male, il senso incarnato della precarietà del vivere.

Cardiac arrhythmias and the role of clinics

Prof. Paolo Della Bella, Director of the Centre for Aritmology of the San Raffaele University Hospital in Milan, known for the clinical view of the problem of cardiac arrhythmias and organisational aspects between doctors and specialised anti-archaemic centres, considers it essential to be clear in a field often underestimated by the practical doctor and thus by the person involved or even overestimated. For example, in the case of abduction, ignoring that it is an exceedance of pharmacology, or in the defibrillator (ICD) where survival is all the greater the less the defibrillator, thanks to the contribution of other associated therapeutic measures (antiarchaemic, abduction, etc.).

The patient’s lifestyle, mental and neurovegetative balance in a harmonious ethical and economic context are always of great importance.

“The battler at night”,is a wake-up call to tell us that something is perhaps changing in our lives. Giuseppe Pontiggia in the Giardino delle Esperidi

Interview with Prof. Paolo Della Bella

By Giuseppe Riggio and Eros Barantani

Night-time arrhythmia is often the first warning call of atrial fibrillation.

At the age of 50 there is a high risk of heart failure and embolia, and perhaps no abduction is needed, but there is a need to think about a “conscientious campaign” and to assess the pathology underlying the arthaemia. Therefore, clinical monitoring (arterial hypertension, obesity, etc.), ecography, Holter with small implantable devices to choose between pharmacological therapy or abduction. Frequent episodes of atrial fibrillation in healthy heart must give us thought to a pathology of the atrio (atrial myocardiopathy), facilitated by the underestimation of arthaemia and by having ignored abduction.

It is necessary to be aware that there are arthmias linked to concurrent factors such as high degree obesity and it is useful to organise a weight control clinic in collaboration with cardiologists’ colleagues.

We know that it is rare (in 5 % of cases) to encourage a dysfunction of the left ventricol, in any case the high frequency of an extrasistolia is poorly tolerated and the detection of an aritmic outbreak by means of an electrophysiological study and appropriate mapping is the most appropriate methodology to prevent major alterations.

At an early stage, ethnicological treatment is important and myocardial biopsy and then immunosoppressive or antiviral treatment should be preferred; the decision is interdisciplinary as a neglected myocarditis becomes dilatative myocardiopathy. It is important to connect with the Padova and Trieste group for a common, multidisciplinary route with aritmologists, electrophysiologists, cardiologi-surgeons for atrial fibrillation, with the aim of personalised treatment such as at the San Raffaele.

Preference in these contexts is to treatment with abduction, which in 80/85 % of cases exceeds any other heart therapy, thus avoiding drug addiction; if the patient has already followed other treatments, the word goes to the technique. When symptoms occur, an electrophysiological study, mapping, abduction should be used. In severe ventricular tachicardie, there are data documenting negative inotropic effects of medicines: CORDARONE in functional class II is useful, in functional class III increases mortality, but has been forced to interrupt the first year in 18 % of cases due to serious problems with hypertyroidism, pulmonary fibrosis; in such cases, there is an indication of the defibrillator’s implantation to solve the sudden death problem. There are no other therapies with such a dramatic impact, but the defibrillator if several times increases mortality, worsens survival; if the applicable strategies increase, they should be followed. The overlap of pharmacological treatment with the defibrillator reduces the number of shocks, the betablocant reduces it by 50 % and the defibrillator, born as a shock box, now has tools to recognise slower ventricular tachicardie and intervene at various frequencies: with frequencies above 200, the number of shocks is reduced so as to support the regression of the arthaemia in a few seconds. Abduction may be used at the same time as or after the defibrillator planting and, in the latter case, the abduction is not followed by increased mortality.

– do not underestimate atrial fibrillation, regardless of ethology, for the damage it causes, in particular celebral damage (cognitive deficit);
– not underestimate the abduction seen as a priority therapy tool over pharmacological therapy;
– do not consider the defibrillator (ICD) to be the solution of severe ventricular arrhythmies due to the positive role of pharmacological association and abduction that avoid damage caused by frequent defibrillator interventions.

Medicina personalizzata: un esempio nella terapia dei tumori

a cura di: Silvio Garattini, Direttore, IRCCS, Istituto di Ricerche Farmacologiche “Mario Negri”, Milano

Il sogno di una medicina personalizzata non è nuovo. Da sempre si ritiene che ci si debba prendere cura dell’ammalato e non della malattia, riconoscendo che le malattie sono una semplificazione diagnostica di una situazione eterogenea. Con il tempo e con lo sviluppo delle tecnologie e delle conoscenze, si sono fatti molti tentativi. Ad esempio, la possibilità di misurare le concentrazioni dei farmaci nel sangue ha permesso di stabilire che la stessa dose dello stesso farmaco dava luogo in differenti soggetti a concentrazioni ematiche molto differenti. Ciò ha fatto pensare alla possibilità di cambiare la dose a seconda della concentrazione ematica per personalizzare il trattamento. I cambiamenti di dose hanno permesso di ottenere qualche risultato positivo, ma in realtà si è poi osservato che eguali concentrazioni di farmaco non permettevano di ottenere una omogeneità di effetti terapeutici.